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Alprine (Alprazolam)

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Alprine is used to treat anxiety and panic disorders. It belongs to a class of medications called benzodiazepines which act on the brain and nerves (central nervous system) to produce a calming effect. It works by enhancing the effects of a certain natural chemical in the body (GABA). Alprine is mostly used to treat anxiety disorders, panic disorders, and nausea due to chemotherapy. Alprine may also be indicated for the treatment of generalized anxiety disorder, as well as for the treatment of anxiety conditions with co-morbid depression. The FDA label advises that the physician should periodically reassess the usefulness of the drug.

Other names for this medication:
Aaram, Alparazole, Alpra, Alpraday, Alsert, Altok, Alzomax, Alzopam, Ambutech, Belfa, Censir, Dazolam, Depflu, Erazol, Esteem, Fludep, Himzolam, Indolam, Morecalm, Parazolam, Pizolam, Prolam, Rescalm, Resolin, Sertakem, Tenfree, Tranisol, Zolark, Zoldac, Zoltweet

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Alprostadil, Cipro, Aricept, Zyloprim, Vermox, Precose, Zudena, Ciprofloxin, Bioxel, Eprotan, Clindareach, Vardif, Rarritol, Metafor, Oprazole,

Also known as: Alprazolam


Alprazolam is used to relieve symptoms of anxiety, including anxiety caused by depression. It is also used to treat panic disorder in some patients.

Alprazolam is a benzodiazepine. Benzodiazepines belong to the group of medicines called central nervous system (CNS) depressants, which are medicines that slow down the nervous system.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain alprazolam. It may not be specific to Alprine. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If too much of this medicine is used for a long time, it may become habit-forming (causing mental or physical dependence) or cause an overdose.

This medicine should come with a Medication Guide. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Swallow the extended-release tablet or tablet whole with a full glass of water. Do not break, crush, or chew it.

If you are using the orally disintegrating tablet, make sure your hands are dry before you handle the tablet. Do not remove the tablets from the bottle until you are ready to take it. Place the tablet immediately on the top of your tongue. It should melt quickly and be swallowed with saliva.

If you are using the oral liquid, measure the dose with a marked measuring spoon, oral syringe, or medicine cup.

Do not eat grapefruit or drink grapefruit juice while you are using this medicine.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For anxiety: For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.25 to 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 4 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For panic disorder: For oral dosage form (extended-release tablets): Adults—At first, 0.5 to 1 milligram (mg) taken in the morning once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.5 mg taken in the morning once a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor.


Seek emergency medical attention if you think you have used too much of this medicine. An overdose of Alprine XR can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, fainting, and coma.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

Detailed Alprine dosage information

Side effects

The most common side effects associated with Alprine are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Studies in women breastfeeding have demonstrated harmful infant effects. An alternative to this medication should be prescribed or you should stop breastfeeding while using this medicine.

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In Situ Delivery of Fibrin-Based Hydrogels Prevents Contraction and Reduces Inflammation. The modeling efforts have led to a refinement in providing mechanistic insight on the accurate prediction of drug and metabolite profiles for DDI, pharmacogenomics, age factors and disease conditions. The model is based on a well-studied experimental system cultured in chemostats (continuous flow-through culture), which consists of rotifer predator, algal prey and nutrient. These may be relatively more important risk factors for stroke among whites and Hispanics than among blacks. Only one aerobic phototrophic strain was isolated from surface waters. In situ hybridization studies demonstrated that the alpha5 subunit mRNA was also strongly decreased in stratum pyramidale of CA1 and CA2. High adiponectin concentrations are associated with the metabolically healthy obese phenotype. The usefulness of a new forced oscillation measuring technique for establishing the airway resistance measured nasally, was investigated in 40 patients. A web-based software library is being developed to handle data storage, analysis and graphic representation. THE EVOLUTIONARY SIGNIFICANCE OF THE SPECIATION OF EUPHRASIA IN EUROPE.

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State-specific smoking-attributable chronic obstructive pulmonary disease mortality--United States, 1986. The outcomes included biochemically validated smoking cessation at 12 months (primary outcome) and changes in cardiovascular risk factor levels and Framingham risk score. Peak oxygen consumption was determined for each test using the following sampling intervals: 60-, 30-, and 15-s averages, eight breath rolling average, and true breath by breath. Our graphical executable scenarios enable user-friendly modeling of temporal processes and retrospective prototyping of decision support on real EHR data. To evaluate the clinical features of respiratory diseases of late preterm neonates. We show that C17ISO homeostasis is regulated by a SREBP-1c-mediated feedback mechanism that is different from the SREBP-1c-mediated regulation of common fatty acid biosynthesis, as well as by peptide uptake and transport.

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Additionally, the different hematopoietic cell lines vary in their level of bisecting GlcNAcylation and antennary fucosylation with the quantities of bisecting N-acetylglucosamine (GlcNAc) and core fucose coinciding with the expression of GnT-III and FucT-VIII. Significant improvement in symptoms, skin test, and specific bronchial reactivity after 6 months of treatment with a depigmented, polymerized extract of Dermatophagoides pteronyssinus and D. However, the effect of positive CM on corneal graft outcome is less known. To examine the role of voided urine endothelin-1 (ET-1) in the diagnosis and follow-up of children with ureteropelvic junction obstruction. Three full-length wt L proteins were expressed in mammalian cells and their ability to form a complex with the MV phosphoprotein was demonstrated. Chronic subdural haematoma (CSDH) is an encapsulated collection of blood and fluid on the surface of the brain.

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Site-directed mutagenesis of the DQ3.2 beta gene was used to convert key nucleotides into DQ3.1 beta codons. In many cases, when applied to inhomogeneous samples, they yield a magnetization decay much slower than that of the Hahn echo. The vast majority of mitochondrial proteins including those of the mitochondrial membranes are nuclear encoded and synthesized as precursor proteins in the cytosol. Recently, with the appearance of new surgical procedures, deep lamellar keratoplasty (DLKP) and deep lamellar endothelial keratoplasty (DLEK), clinicians should re-evaluate the value of lamellar keratoplasty. Ovarian serous cystadenofibromas are benign neoplasms that sometimes have focal areas of borderline serous tumor and rarely have been associated with epithelial proliferations in the peritoneum, resembling implants. We also compare the starvation and desiccation resistance of individuals that exchange respiratory gases continuously with those that breathe discontinuously.

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Evaluation of targeted therapies, however, is a relatively recent development. The 3 cultivars tested were grown under the same conditions in an experimental field (SE Spain) where they were not previously cultivated since these cultivars are typical of cold, Northern-European areas. Climato-economic livability predicts societal collectivism and political autocracy better than parasitic stress does. Binding characteristics of pancreatic polypeptide receptors on rat hepatic membranes. Venous thromboembolism in Pakistan: a neglected research agenda. Cigarette smoking among 40-year-old residents living in Poznan and its Province.

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Confocal immunofluorescence microscopy revealed that the protein is located exclusively in the cytoplasm, probably in the endoplasmic reticulum. pylori is a potential cause of C1-INH deficiency observed in our case. Using a novel setup, we assessed how fast growth of Nicotiana tabacum seedlings responds to alterations in the light regime and investigated whether starch-free mutants of Arabidopsis thaliana show decreased growth potential at an early developmental stage. In the adult patients, sloping of distal tibial articular surface associated with degenerative changes of both hip joints is a reliable diagnostic sign. Impact of race on treatment response and cardiovascular disease among hypertensives. The viability of treated cells was determined by the colorimetric MTS assay. Chronic hepatitis B virus (HBV) infection and dietary exposure to aflatoxin B1 (AFB1), two of the major risk factors in the multifactorial aetiology of hepatocellular carcinoma (HCC), co-exist in those countries with the highest incidences of and the youngest patients with this tumour, raising the possibility of a synergistic carcinogenic interaction between the two agents.

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The reactor which represented the characteristics of young landfill was operated under four operational stages to enhance the activity of methanogenic population and accelerate waste stabilization. The extracts preserved the antigenic activity after enzyme hydrolysis with pronase. Clinical implication and prognostic significance of the tumor suppressor TSLC1 gene detected in adenocarcinoma of the lung. This study examined the impact of media consumption, and particularly exposure to television, on decisions regarding interest rate demands. Reduced drug prices, targeting polyarthritis patients or reducing rheumatology visit frequencies may improve value for money metrics in future studies. Trophectoderm (TE) is the first cell type that emerges during development and plays pivotal roles in the viviparous mode of reproduction in placental mammals. However, reports that over half of patients who underwent a virilizing puberty adopted an adult male gender identity have challenged this practice.

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miRNAs have recently been shown to have important roles in human organ transplantation, but reports of miRNAs directly associated with corneal transplantation rejection remain limited. Of the three tag-SNPs genotyped, rs4544 polymorphism was monomorphic and rs3802230 deviated Hardy-Weinberg equilibrium. Two physiotherapists working within-scope conducted a telephone triage (October to December 2010) using a standard instrument for all new patients on the orthopedic waiting list. Caesarean section and tubal infertility: is there an association?. The expression of telomerase activity has a significant relationship to carcinogenesis. Substances exhibiting maximum hypoglycemic activity were additionally characterized by the acute toxicity and the hypoglycemic effect on the model of alloxan diabetes in rats. However, translating the results of a trial into clinical care can be complex due to the intrinsic tension between the requirements for scientific methods that minimize systematic and random error, and the need for clinically relevant and generalizable data. Although parameters such as hospitalization duration, transfusion requirements and surgery rates have improved with advances in endoscopic therapy, mortality rates remain relatively static. The review will be prepared according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement, the Cochrane methodology and the Grading of Recommendations, Assessment, Development and Evaluation.

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Evidence shows that LLLT can secondarily enhance neural metabolism by regulating mitochondrial function, intraneuronal signaling systems, and redox states. Non-pharmacologic strategies in hematopoietic stem cell transplantation. Antimicrobial photodynamic therapy (aPDT) is a nonantibiotic broad-spectrum antimicrobial treatment that has been demonstrated to eradicate antibiotic-resistant bacteria and biofilms. Body temperature and behavior of tree shrews and flying squirrels in a thermal gradient. Pharmacogenetics of smoking cessation: role of nicotine target and metabolism genes. Theoretical prediction of a time-at-pressure curve for avoiding pressure sores. The latter finding strongly suggests an involvement of PARP in the repair of DNA double-strand breakage. Though heterogeneous, these studies reported an overall favorable outcome in carefully selected patients with topographically limited pain syndromes. Here we investigate whether changes in the metabolic profile of PCOS women are driven by increased tendency to obesity or are specific features of PCOS related to increased testosterone levels. Thus, genetic risk factors play a critical role in the reinforcing efficacy of MA and the oral self-administration procedure is suitable for delineating genetic contributions to MA reinforcement.

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The antitoxins are proteins or antisense RNAs that counteract the toxins. The prevalence of development defects of enamel and dental caries in New Zealand children receiving differing fluoride supplementation, in 1982 and 1985. However, a lack of understanding of the nature of the assays and the laboratory assignment of normal versus abnormal often leads to unnecessary workup or missed disease. In the present study, malformed ears of monkey fetuses exposed to RA during early embryogenesis were analyzed and revealed a subtype of defects., i.e., apparent duplication of the external/middle ear. This study determined the bond strengths of porcelain bonding systems joined to a ceramic material, with the aim of evaluating the effect of a catalyst for silane coupling as well as that of initiators for bonding agents. Primary prevention of this disease relies on ventilation and good use practices. After three courses of the chemotherapy, computed tomography showed that the tumor at the hepatic hilum was no longer visible and that the serum CA19-9 level was reduced to normal. The control group also provided the opportunity for preliminary assessment of the efficacy of the transplantation. Effect of exercise intensity on the postexercise sweating threshold. The optimum range of the volumetric activity of this substance and its daughter degradation products, and their generated aeroions is substantiated.

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To assess the national prevalence of low levels of high-density lipoprotein cholesterol (HDL-C) among adults with coronary heart disease (CHD) and the relationship between low HDL-C and predicted rates of recurrent CHD events. Admission to care: facilitating role transition amongst family carers. All are fairly reproducible and have been applied successfully in monitoring neurogenic disease progression. There is a critical need to estimate dietary folate intakes for nutrition monitoring and food safety evaluations, but available intake data are seriously limited by several factors. Serum CRP level before chemotherapy might be a potential prognostic factor for MGC. A positive response after treatment 1 tended to predict similar responses to subsequent treatments, whereas a lack of response to treatment 1 did not preclude positive response(s) to later treatments. Eight hospitals with co desyrel 25 mg -located EDs and walk-in centres were compared with eight matched EDs without walk-in centres. Randomized, placebo-controlled studies to final adult height have proven that GH therapy is effective in increasing stature in TS. Academy members are concerned about preventing these high risk errors.

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Extramedullary disease at diagnosis of AML does not influence outcome of patients undergoing allogeneic hematopoietic cell transplant in CR1. The study was based on 5,538 nurses in the age of 51-59 who in 1993 completed a questionnaire on health, lifestyle, working environment, and sociodemographic factors. The structures of the compounds 4a-4g were established by the combined use of (1)HNMR, IR and mass spectra. Serum and myocardial carnitine levels in the animals with diabetes and reduced myocardial function were low. Pedunculated solitary fibrous tumor of the interlobar fissure: a wandering chest mass. Metagenomic analysis is urgently needed to better understand those complex communities in CF pulmonary infections. This study examined whether oxidative DNA damage and its repair system contribute to the occurrence of diabetes in an experimental rat model. Older AEDs, such as phenytoin and carbamazepine, may not be indicated in JME patients. Impairment of the inflammatory reaction on implanted Taenia solium metacestodes in mice by a T. Palliative thyroidectomy relieved airway compromise in the second case.

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Five adult broiler breeders were inoculated with faeces and tissue extracts from birds with big liver and spleen (BLS) disease. We report a case of a woman presenting a giant cementoossifying fibroma depending of the mandibular gingivae. Changes in regional tissue oxygenation saturation and desaturations after red blood cell transfusion in preterm infants. Implementation of an enhanced recovery protocol in pediatric colorectal surgery. We defined an intubation time difference of less than 10 s as clinically insignificant. In 60 cases intracapsular resection of goiter was performed by using ultrasonic aspirator.

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Analysis of the results of clinical surveys and trials suggests that individual definitions of anemia and choice of the study population have a major influence on estimating the prevalence of anemia in patients with chronic heart failure. The results showed that data reduction with high signal fidelity can thus be achieved with average data compression ratio of 25.2:1 and average PRD of 3.14. Nevertheless, although it has taken decades to convince ourselves that elderly people belong to a specific age group both biologically and medicinally, and in whom special criteria have to be taken into consideration, it seems that even they themselves do not present an homogenous group. The semi-suspended bio-carrier caused three different mass transfer zones occurring in the do progesterone pills cause cramps bioreactor, including the zones of bulk solution, boundary layer and biofilm, in which, the boundary layer zone had an obvious higher mass transfer resistance. To our knowledge, this is the first case of vulvar epithelioid sarcoma described in the MRI literature. How well are endoscopes cleaned and disinfected between patients?. The radiographic and clinical findings were typical, appearing as a well-defined radiolucent-radiopaque lesion coronal to an erupting permanent tooth. One patient subsequently received a third-generation cephalosporin, ceftriaxone (Rocephin, Roche), without adverse reaction. Immunoblots of nuclear extracts confirm the Jak2 nuclear exclusion.

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Post-Transplant Hypophosphatemia and the Risk of Death-Censored Graft Failure and Mortality after Kidney Transplantation. SMANCS-TAE under balloon occlusion of the corresponding hepatic vein, which can also embolize the portal vein by applying targeting chemotherapy with SMANCS, may cause necrosis not only in the tumor but also in noncancerous liver tissues. It shows a new combination of Chido and Rodgers antigenicities and expresses reverse antigenicity because it carries Rodgers 1, 2, and 3. In addition, Tpx2 haploinsufficiency led to the accumulation of aneuploidies in vivo and increased susceptibility to spontaneous lymphomas and lung tumors. Regular colloidal crystals, obtained by a modified Langmuir-Blodgett approach, are used as templates for the electrogeneration of the desired metals in the form of a well-defined layered bimetallic porous electrode. The persistence of rabies virus antibodies in the sera of fox cubs.

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Increased concentrations (1 X levaquin dosage instructions 10(-4) M) of ACh completely abolished excitability. We analyzed the factors associated with the recurrence and survival of CMHN patients treated in our institution. Morbidity, mortality, and cost were evaluated using multivariable logistic and linear regression models. Given that T cell p38 may play a role in Th1 development, the response to Th-skewing Ags was analyzed in Gadd45alpha(-/-) mice. Patterns of relapse and response to retreatment in patients with metastatic melanoma or renal cell carcinoma who responded to interleukin-2-based immunotherapy. Furthermore, the full-length TonB was shown to form a 1:1 complex with either apo-ShuA H86A/H420A or the wild-type ShuA. Regional subdivision in wild barley allozyme variation: adaptive or neutral?. These findings suggest that HY accelerates the healing process in tooth sockets of rats stimulating the expression of osteogenic proteins.

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Hence the C52L fusion inhibitor may find a practical application, for example as a vaginal or rectal microbicide to prevent HIV-1 infection in the developing world. Microtubule-associated protein 2 (MAP2) belongs to the family of heat stable MAPs, which takes part in neuronal morphogenesis, maintenance of cellular architecture and internal organization, cell division and cellular processes. Measuring creatine kinase MB isoenzyme in a maintenance hemodialysis population: chemiluminometric immunoassay and electrophoresis compared. In addition, 200 mL orange juice or water was ingested at 4, 10, 22, and 27 hours after celiprolol intake. Early induction of humoral and cellular immune responses during experimental Mycobacterium avium subsp. We analyzed the subcellular distribution of Kv2.2 protein within single cultured neurons. In the future angiogenesis inhibitors, like insulin therapy in diabetes, may be used to inhibit tumour growth and to induce stabilization of the disease. However, no patients with HNF-1 beta mutations have biliary manifestations.

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Results showed that the expression of HCB in hemocytes exhibited developmental stage specificity. Intraepithelial macrophages increased in number during involution, developed cytoplasmic lipofuscin pigment, and either remained within the epithelium or migrated to the interstitium and regional nodes. Effects of enflurane on ectopic automaticity induced by local injury. The observations made in these two experiments show the importance of venereal spread of M. Utilization of hydrogen bonds to stabilize M-O(H) units: synthesis and properties of monomeric iron and manganese complexes with terminal oxo and hydroxo ligands. Our study suggests reciprocal regulation of PlncRNA-1 and androgen receptor contribute to CaP pathogenesis and that PlncRNA-1 is a potential therapy how long does diflucan 150 mg take to work target.

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However, most studies have focused on an average volume per specific time period and have paid little attention to the pattern of drinking. Building an active citizenry: the role of neighborhood problems, readiness, and capacity for change. The biopsies were obtained from patients undergoing investigations for infertility. The present study demonstrated that O-HTCC-SOD had wider pH activity range, better thermal stability, excellent long-term stability for storage, as well as unique reinstatement of activity exposure to proteolytic degradation that was helpful for longer half-life in vivo. In addition, we examined the expression of a gene coding for those MyHC proteins. These results support the idea of systemic susceptibility, and infection through a common agent such as HPV, contributing to the cause of SSC. These structures are found to be consistent with available mechanistic data, and are also compatible with X-ray diffraction models and extended X-ray absorption fine structure measurements.

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Retrospective interrogation of a prospectively maintained Complaints Department database at a University Hospital for the calendar year 2009. This technique provides a simple and precise method for the evaluation of the accuracy of DBS electrode placement. Twenty seven subjects performed isometric maximal knee extension contractions and contractions induced by electrostimulation on a dynamometer. We report a family with five of six siblings (including identical male twins) with a novel constellation of immunologic and neurologic impairments. Prevention of postoperative nausea and vomiting after hysterectomy with oral dolasetron, intravenous dehydrobenzperidol or a combination of both substances. Furthermore, the tested mice were found to have significantly increased delayed- singulair 5 mg side effects type hypersensitivity, plaque-forming cells, and half-hemolysis values after the intervention with the fermented milk. Degradation mechanism of t-butyl methyl ether (MTBE) in atmospheric droplets. Plasma glucose and bicarbonate levels were 27.0 mmol/l and 5 mmol/l, respectively. To determine the effect of anti-inflammatory medications on 30-day survival of dogs treated for pulmonary blastomycosis. GBV-C NS3 serine protease significantly inhibited HIV replication without decreasing HIV receptor expression.

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